Proteomics and Molecular Medicine

Mass spectrometry (MS) - based proteomics allows the sensitive and accurate quantification of almost complete proteomes of complex biological fluids and tissues. At the moment, however, the routinely usage of MS-based proteomics is prevented and complicated by the very complex work flow comprising sample preparation, chromatography, MS measurement followed by data processing and evaluation. The new technologies, products and assays developed by Precision Proteomics could help enabling and establishing mass spectrometry (MS) - based proteomics in academic and pharmaceutical proteomics research as well as in clinical diagnostics.

Molecular Medicine promotes the thoughtful of biological mechanism of disease at the cellular and molecular levels for enhanced diagnoses, treatment, and prevention of disease. Proteomics plays an important role in medical research and molecular medicine, such as in drug discovery and diagnostics, because of the link between proteins, genes and diseases, and it is considered to be the next step in modern biology. Proteomics is dynamic compared to genomics because it changes constantly to reflect the cell’s environment. The main objectives in the arena of proteomics are; identifying all proteins, analyse differential protein expression in different samples, characterise proteins by identifying and studying their function and cellular localisation, and recognize protein interaction networks.

Molecular diagnostics is prominent disruptive innovation in healthcare by the introduction of many tools that are having a profound impact on healthcare delivery. These include next-generation sequencing, wearable sensors, liquid biopsies, direct-to-consumer testing, point-of-care assays, and early cancer detection. Join industry leaders at the molecular diagnostics event to discuss recent developments and decipher how changes in regulation, reimbursement, and implementation guidelines will impact progress in new markets created by innovations in this technology.

Molecular diagnostics and devices are enabling precise diagnosis and treatment of oncology, infectious disease and immunotherapy. Experts in the arena will highlight the latest tools, clinical advances, besides commercial applications of circulating and tissue-based biomarkers that are transforming medicine.

Protein expression refers to the way in which proteins are synthesized, modified and regulated in living organisms. In protein research, the term can apply to either the object of study or the laboratory techniques required to manufacture proteins. Protein analysis is the bioinformatics study of protein structure, protein interaction and function using database searches, sequence comparisons, structural and functional predictions.

Personalised medicine aims to tailor treatments to achieve the best outcome for individual patients, rather than treating patients with a ‘one size fits all’ approach. Personalized medicine, also termed precision medicine, is a medical procedure that separates patients into different groups—with medical decisions, practices, interventions and/or products being tailored to the individual patient based on their predicted response or risk of disease.

Biochemistry is the study of the structure and function of biological molecules such as proteins, nucleic acids, carbohydrates and lipids. Biochemistry is also used to describe techniques suited to understanding the interactions and functions of biological molecules and it is a laboratory based science that brings together biology and chemistry. By using chemical knowledge and techniques, biochemists can understand and solve biological problems. Biochemistry focuses on processes happening at a molecular level and it focuses on what’s happening inside our cells. It also looks at how cells communicate with each other, for example during growth or fighting illness. Medicine is a broad category but relates to biochemistry on many levels. Doctors and nurses give drugs to patients to help cure a disease or prevent it. This is since when that drug is added to the human system, it alters how other chemicals in the body function, resulting in disease prevention or recovery.

The significance and role of the human genome in the diagnosis and treatment of disease, they lay out the groundwork for precision or genomic medicine. In turn, immuno-oncology researches are changing the way we treat cancer by unleashing the immune system, and achieving better survival for many patients and cure for some. Covering latest advances in precision medicine, genomics and genetics for drug discovery application, cancer immuno-therapy, biomarkers and translational strategies in immune-oncology, Precision Medicine and Immuno-Oncology tracks will bring together uppermost experts from industry and academia to discuss emerging trends and solutions in order to provide the most up-to-date, scientifically sound care for patients with cancer and chronic diseases.

Systems biology is an exciting new approach to understand biological complexity. It builds on large-scale measurement technologies, such as next-generation sequencing and mass spectrometry.

Bioinformatics is both an umbrella term for the body of biological studies that use computer programming as part of their methodology, as well as a reference to specific analysis "pipelines" that are repeatedly used, particularly in the fields of genetics and genomics. Common uses of bioinformatics include the identification of candidate genes and nucleotides.

Proteins provide most of the molecular machinery of cells. Many are enzymes or subunits of enzymes. Other proteins play structural or mechanical roles, such as those that form the struts and joints of the cytoskeleton. Each protein is linear polymers built of amino acids.