Protein Sequencing & Molecular Interactions

Protein sequencing is the practical process of determining the amino acid sequence of all or part of a protein or peptide. This may serve to identify the protein or characterize its post-translational modifications. Typically, partial sequencing of a protein provides sufficient information (one or more sequence tags) to identify it with reference to databases of protein sequences derived from the conceptual translation of genes.

Molecular Interactions are attractive or repulsive forces between molecules and between non-bonded atoms. Molecular interactions are important in diverse fields of protein folding, drug design, material science, sensors, nanotechnology, separations, and origin of life. Molecular interactions are also known as non-covalent interactions or intermolecular interactions. Molecular interactions are not bonds.

  • Determining amino acid composition
  • N-terminal amino acid analysis
  • C-terminal amino acid analysis
  • Edman degradation
  • Identification by mass spectrometry
  • Predicting from DNA/RNA sequences

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